Global Meso PDRN

It represents a new era in non-invasive rejuvenation and cellular skin restructuring. This specialized in-office treatment is designed for mature, sagging, sun-damaged skin that requires immediate repair and regenerative stimulation. Tissue aging impairs natural cell division mechanisms, leading to thinning of the epidermis and the formation of wrinkles. The cocktail’s action is based on the delivery of nucleotides, which act as bio-renewers of the DNA matrix. The product not only visually smooths the surface of the face but also stimulates fibroblast metabolism, accelerating the physiological remodeling of the skin. The result of a series of treatments is a noticeable thickening of the skin’s structure, improved density, optimal hydration, and a youthful, healthy glow.

Key actions and properties

• Deep cellular regeneration – activates the synthesis of endogenous DNA, accelerating tissue healing and reconstruction.
• Intensive biorevitalization – stimulates fibroblasts to dynamically produce collagen and elastin fibers.
• Smoothing and wrinkle reduction – reduces epidermal creases caused by natural aging and photoaging.
• Deep tissue hydration – restores and maintains proper moisture levels in the deeper layers of the skin.
• Epidermal renewal – accelerates cell keratinization, improving texture and evening out skin tone.

Active ingredients

• Sodium DNA (PDRN / Polynucleotides) – nucleic acid fractions that stimulate adenosine receptors in cells; they initiate intensive tissue repair and have strong anti-inflammatory and regenerative effects.
• Sodium Hyaluronate (Hyaluronic Acid) – a high-molecular-weight humectant with excellent water-binding properties; provides an immediate plumping effect, hydrates, and improves the elasticity of the epidermis.
• Retinol (Pure Vitamin A) – a powerful stimulator of cell renewal; exfoliates dead skin cells, regulates melanocyte activity, and directly stimulates the production of new collagen.
• Tocopherol / Tocopheryl Acetate (Vitamin E) – a natural antioxidant that stabilizes the action of retinol, protects epidermal lipids from oxidation, and strengthens the hydrolipid barrier.

How to use

• Intended Use: This product is intended exclusively for professional use in beauty salons, cosmetology clinics, and aesthetic medicine practices.
• Application Techniques: Recommended for treatments using microneedle mesotherapy (Dermapen, rollers) and non-invasive transdermal methods (iontophoresis, sonophoresis, electroporation, needle-free mesotherapy).
• Areas of application: Face, neck, décolleté, hands, and any areas of the body requiring immediate anti-aging therapy and strong structural restoration.
• Procedure: Apply a measured dose of the product to sterile, disinfected skin immediately before or during the device-based treatment / microneedling.
• Frequency: To achieve lasting tissue restructuring effects, a series of 4–5 treatments is recommended at intervals of 2–3 weeks.