A sterile solution for professional use, serving as a key element of MeLine’s depigmenting therapy. The product was developed for transdermal administration (e.g., via microneedling or electroporation), allowing the active ingredients to reach the skin layers where pigment overproduction occurs.

The preparation works comprehensively: it not only lightens existing discoloration but also regulates tyrosinase enzyme activity, preventing the formation of new lesions. The formula is particularly effective in difficult cases of vascular and hormonal discoloration. Systematic use as part of the MeLine protocol allows for a lasting effect of a radiant, even complexion without the risk of severe irritation.

Key actions and properties

• Powerful depigmentation: Inhibits the melanogenesis process at several stages.
• Inflammation reduction: Reduces the vascular component of hyperpigmentation (common in melasma).
• Antioxidant action: Protects cells from UV-induced oxidative stress.
• Improved skin texture: Stimulates cell renewal, smoothing the epidermis.
• High bioavailability: Optimal acid concentrations for delivery via instrumental methods.

Active ingredients

• Tranexamic Acid: Inhibits the formation of vascular-based hyperpigmentation and blocks the interaction between melanocytes and keratinocytes.
• Glutathione: A powerful antioxidant that switches melanin synthesis to a lighter pigment (pheomelanin).
• Ascorbic Acid (Vitamin C): Brightens the skin and neutralizes free radicals.
• Aminoethylphosphinic Acid: Inhibits the enzymatic stages of pigment formation.
• Sodium Hyaluronate (Hyaluronic Acid): Provides hydration and regeneration during the treatment.

How to use

• Cleanse the skin and prepare it using MeLine 00 Prep.
• MeLine 01 ID should be administered using professional transdermal techniques:
• Microneedle mesotherapy (Dermapen): Punctures to a depth adjusted to skin thickness (typically 0.25–0.5 mm).
• Electroporation / Iontophoresis: Use of electrical current to transport molecules.
• After applying the solution, apply a soothing mask or an occlusive product recommended by the manufacturer.
• Note: This product is intended exclusively for professional use by physicians or qualified cosmetologists.